The 4100 ships with one cleaning mode: Clean. There is no Sensitive, White, Gum Health, or Deep Clean option. Whether this reads as a limitation or a feature depends entirely on how you brush and what you're looking for.
For the majority of everyday users, a single well-calibrated cleaning mode is sufficient. The added complexity of mode-switching is something many people simply never use, even on brushes that offer it. In that context, removing the choice makes the product more reliable to use correctly every single day.
However, users who have been advised to use a gentler brushing action for gum sensitivity, or who are working on targeted stain removal, will find the 4100 inflexible. Sonicare's own 5100 adds a Sensitive mode and a Gum Care mode for a moderate price increase, which may be worth it if your oral care needs are specific.
The single-mode approach also means the 4100 ages less gracefully than premium models as your oral care needs change. It's best thought of as a committed entry-level product rather than one that grows with you.